发明授权
- 专利标题: Hydroxamic acid derivatives useful as antibacterial agents
- 专利标题(中): 羟肟酸衍生物可用作抗菌剂
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申请号: US13119484申请日: 2009-09-01
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公开(公告)号: US08722686B2公开(公告)日: 2014-05-13
- 发明人: Matthew F. Brown , Charles F. Donovan , Edmund L. Ellsworth , Denton W. Hoyer , Timothy A. Johnson , Manjinder S. Lall , Chris Lim-Berakis , Sean T. Murphy , Debra A. Sherry , Clarke B. Taylor , Joseph S. Warmus
- 申请人: Matthew F. Brown , Charles F. Donovan , Edmund L. Ellsworth , Denton W. Hoyer , Timothy A. Johnson , Manjinder S. Lall , Chris Lim-Berakis , Sean T. Murphy , Debra A. Sherry , Clarke B. Taylor , Joseph S. Warmus
- 申请人地址: US NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: US NY New York
- 代理商 John A. Wichtowski
- 国际申请: PCT/IB2009/053809 WO 20090901
- 国际公布: WO2010/032147 WO 20100325
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K31/67 ; A61K31/165 ; A61K31/415 ; A61K31/535 ; C07D239/42 ; C07D413/02 ; C07D239/02 ; C07D491/02 ; C07D213/56 ; C07D277/30 ; C07D261/06 ; C07D403/02 ; C07D233/54 ; C07D307/02 ; C07D235/02
摘要:
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L1-L4 A, B, R1-R4 and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.
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