发明授权
US08735124B2 Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
有权
分离的PON1多肽，编码它们的多核苷酸及其在治疗或预防有机磷酸盐暴露相关损伤中的用途
- 专利标题： Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
- 专利标题（中）： 分离的PON1多肽，编码它们的多核苷酸及其在治疗或预防有机磷酸盐暴露相关损伤中的用途
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申请号： US13420920申请日： 2012-03-15
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公开(公告)号： US08735124B2公开(公告)日： 2014-05-27
- 发明人: Dan S. Tawfik , Rinkoo Devi Gupta , Moshe Goldsmith , Yaacov Ashani
- 申请人： Dan S. Tawfik , Rinkoo Devi Gupta , Moshe Goldsmith , Yaacov Ashani
- 申请人地址： IL Rehovot
- 专利权人： Yeda Research and Development Co. Ltd.
- 当前专利权人： Yeda Research and Development Co. Ltd.
- 当前专利权人地址： IL Rehovot
- 主分类号： C12N9/16
- IPC分类号： C12N9/16 ; C12N9/14 ; C12P21/06 ; C12P19/34 ; C12N15/00 ; C07H21/04 ; C07K1/00 ; A01N25/34 ; A61K9/00 ; A61K38/46
摘要：
An isolated polypeptide comprising the amino acid sequence of serum paraoxonase (PON1) having catalytic efficiency of kcat/KM≈106-5·107 M−1min−1 for a G-type organophosphate.
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