Invention Grant
- Patent Title: Spiroxazolidinone compounds
- Patent Title (中): 螺恶唑烷酮化合物
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Application No.: US13810946Application Date: 2011-08-12
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Publication No.: US08742110B2Publication Date: 2014-06-03
- Inventor: Joseph L. Duffy , Jianming Bao , Debra L. Ondeyka , Sriram Tyagarajan , Patrick Shao , Feng Ye , Revathi Katipally , Aaron Zwicker , Edward C. Sherer , Michael A. Plotkin , Remond Moningka , Zahid Hussain , Harold B. Wood , Feroze Ujjainwalla , F. Anthony Romero , Paul E. Finke , Yi Zang , Weiguo Liu
- Applicant: Joseph L. Duffy , Jianming Bao , Debra L. Ondeyka , Sriram Tyagarajan , Patrick Shao , Feng Ye , Revathi Katipally , Aaron Zwicker , Edward C. Sherer , Michael A. Plotkin , Remond Moningka , Zahid Hussain , Harold B. Wood , Feroze Ujjainwalla , F. Anthony Romero , Paul E. Finke , Yi Zang , Weiguo Liu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; Catherine D. Fitch
- International Application: PCT/US2011/047590 WO 20110812
- International Announcement: WO2012/024183 WO 20120223
- Main IPC: C07D215/00
- IPC: C07D215/00 ; C07D229/00 ; A61K31/44 ; A61K31/397
Abstract:
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.
Public/Granted literature
- US20130131042A1 SPIROXAZOLIDINONE COMPOUNDS Public/Granted day:2013-05-23
Information query
