Invention Grant
- Patent Title: Oligomer-calcium channel blocker conjugates
- Patent Title (中): 寡聚体 - 钙通道阻断剂共轭物
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Application No.: US12674139Application Date: 2008-09-03
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Publication No.: US08748648B2Publication Date: 2014-06-10
- Inventor: Zhongxu Ren , Bo-Liang Deng , Jennifer Riggs-Sauthier , Micah Harvey
- Applicant: Zhongxu Ren , Bo-Liang Deng , Jennifer Riggs-Sauthier , Micah Harvey
- Applicant Address: US CA San Francisco
- Assignee: Nektar Therapeutics
- Current Assignee: Nektar Therapeutics
- Current Assignee Address: US CA San Francisco
- Agent Timothy A. Marquart
- International Application: PCT/US2008/010385 WO 20080903
- International Announcement: WO2009/032286 WO 20090312
- Main IPC: C07C255/00
- IPC: C07C255/00
Abstract:
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.
Public/Granted literature
- US20110098273A1 Oligomer-Calcium Channel Blocker Conjugates Public/Granted day:2011-04-28
Information query
