Hydroxylated tricyclic compounds
    1.
    发明授权
    Hydroxylated tricyclic compounds 有权
    羟基化三环化合物

    公开(公告)号:US09090535B2

    公开(公告)日:2015-07-28

    申请号:US13992587

    申请日:2011-12-09

    CPC分类号: C07C217/52

    摘要: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water-soluble oligomer.

    摘要翻译: 本发明提供通过共价连接水溶性低聚物进行化学修饰的小分子药物。 本发明化合物当通过多种施用途径中的任一种施用时,显示出与未附着于水溶性低聚物的小分子药物的特性不同的特征。

    Oligomer-anticholinergic agent conjugates
    10.
    发明授权
    Oligomer-anticholinergic agent conjugates 有权
    寡聚物 - 抗胆碱能药物缀合物

    公开(公告)号:US08389759B2

    公开(公告)日:2013-03-05

    申请号:US12530424

    申请日:2008-03-12

    IPC分类号: C07C69/76 C07C69/74

    CPC分类号: C07C69/736 A61K47/60

    摘要: The invention provides anticholinergic agents that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different as compared to the characteristics of the anticholinergic agent not attached to the water-soluble oligomer.

    摘要翻译: 本发明提供通过共价连接水溶性低聚物进行化学修饰的抗胆碱能药。 本发明的缀合物当通过多种施用途径中的任一种施用时,显示出与未附着于水溶性低聚物的抗胆碱能药物的特征相比不同的特征。