发明授权
- 专利标题： Peptides for inhibiting transglutaminase
- 专利标题（中）： 用于抑制转谷氨酰胺酶的肽
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申请号： US11918340申请日： 2006-10-11
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公开(公告)号： US08754033B2公开(公告)日： 2014-06-17
- 发明人: Soo youl Kim , In hoo Kim , Sung soo Park
- 申请人： Soo youl Kim , In hoo Kim , Sung soo Park
- 申请人地址： KR Gyeonggi-Do
- 专利权人： National Cancer Center
- 当前专利权人： National Cancer Center
- 当前专利权人地址： KR Gyeonggi-Do
- 代理机构： Casimir Jones, S.C.
- 代理商 Tanya A. Arenson
- 优先权： KR10-2005-0124420 20051216
- 国际申请： PCT/KR2006/004089 WO 20061011
- 国际公布： WO2007/069817 WO 20070621
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12Q1/00 ; C12N9/00 ; C12N9/99 ; C12N1/20 ; C12N15/00 ; C07H21/04
摘要：
Disclosed herein are transglutaminase peptide inhibitors which have inhibitory activity against transglutaminase, and a pharmaceutical composition comprising one of them as an active ingredient. The inhibitors or the composition is useful in the prevention and treatment of various diseases caused by aberrant transglutaminase activation, including inflammatory diseases and cancers. Also, methods for treating various inflammatory diseases and cancers and for preparing mutant peptides capable of inhibiting transglutaminase are also disclosed.
公开/授权文献
- US20090197812A1 Peptides for Inhibiting Transglutaminase 公开/授权日：2009-08-06
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