发明授权
US08759537B2 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
有权
3H-咪唑并[4,5-C]吡啶-6-甲酰胺作为抗炎剂
![3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents](/docs/US/2014-06-24/US08759537B2/abs.jpg.600x600.jpg)
- 专利标题： 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
- 专利标题（中）： 3H-咪唑并[4,5-C]吡啶-6-甲酰胺作为抗炎剂
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申请号： US13211470申请日： 2011-08-17
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公开(公告)号： US08759537B2公开(公告)日： 2014-06-24
- 发明人: Henning Priepke , Henri Doods , Raimund Kuelzer , Roland Pfau , Dirk Stenkamp , Benjamin Pelcman , Robert Roenn
- 申请人： Henning Priepke , Henri Doods , Raimund Kuelzer , Roland Pfau , Dirk Stenkamp , Benjamin Pelcman , Robert Roenn
- 申请人地址： DE Ingelhein am Rhein
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： DE Ingelhein am Rhein
- 代理商 Michael P. Morris; Philip I. Datlow
- 优先权： EP10173501 20100820
- 主分类号： A61K31/427
- IPC分类号： A61K31/427 ; A61K31/428 ; A61K31/422 ; A61K31/4439 ; C07D401/12 ; C07D403/12 ; C07D413/12 ; C07D235/30 ; C07D417/12
![3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents](/abs-image/US/2014/06/24/US08759537B2/abs.jpg.150x150.jpg)
摘要：
This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R6, R7, R8 have meanings given in the description.
公开/授权文献
- US20120214786A1 NEW COMPOUNDS 公开/授权日：2012-08-23
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