Invention Grant
- Patent Title: Kinase inhibitors, compositions thereof, and methods of use therewith
- Patent Title (中): 激酶抑制剂，其组合物及其使用方法
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Application No.: US12135575Application Date: 2008-06-09
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Publication No.: US08765802B2Publication Date: 2014-07-01
- Inventor: Robert Shoemaker , John Cardellina , Michael Currens , Sudhir Kondapaka , Yves Pommier , Andy Jobson , Dominic Scudiero , David Waugh , George Lountos , Charles M. Cook , Guangtao Zhang , Andrew Colasanti , Christopher R. Self
- Applicant: Robert Shoemaker , John Cardellina , Michael Currens , Sudhir Kondapaka , Yves Pommier , Andy Jobson , Dominic Scudiero , David Waugh , George Lountos , Guangtao Zhang , Andrew Colasanti , Christopher R. Self , Janet Cicariello Cook
- Applicant Address: US NJ Monmouth Junction US DC Washington
- Assignee: Provid Pharmaceuticals, Inc.,United States of America as represented by the Department of Health and Human Resources NIH
- Current Assignee: Provid Pharmaceuticals, Inc.,United States of America as represented by the Department of Health and Human Resources NIH
- Current Assignee Address: US NJ Monmouth Junction US DC Washington
- Agency: Jones Day
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D209/42
Abstract:
Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
Public/Granted literature
- US20090018141A1 KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH Public/Granted day:2009-01-15
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