- 专利标题： Polycyclic compounds as lysophosphatidic acid receptor antagonists
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申请号： US12893902申请日： 2010-09-29
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公开(公告)号： US08778983B2公开(公告)日： 2014-07-15
- 发明人: Ryan Clark , Brian Andrew Stearns , Lucy Zhao , Thomas Jon Seiders , Deborah Volkots , Jeannie M. Arruda , David Nathan Zalatan
- 申请人： Ryan Clark , Brian Andrew Stearns , Lucy Zhao , Thomas Jon Seiders , Deborah Volkots , Jeannie M. Arruda , David Nathan Zalatan
- 申请人地址： US NJ Princeton
- 专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人地址： US NJ Princeton
- 代理商 Maureen S. Gibbons
- 主分类号： A61K31/4192
- IPC分类号： A61K31/4192 ; C07D413/06 ; C07D413/12
摘要：
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
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