Invention Grant
US08784862B2 Compounds and method for coating surfaces in a hemocompatible manner
有权
以血液相容的方式涂覆表面的化合物和方法
- Patent Title: Compounds and method for coating surfaces in a hemocompatible manner
- Patent Title (中): 以血液相容的方式涂覆表面的化合物和方法
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Application No.: US12827710Application Date: 2010-06-30
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Publication No.: US08784862B2Publication Date: 2014-07-22
- Inventor: Roland Horres , Marita Katharina Linssen , Michael Hoffmann , Erika Hoffmann , Donate DiBiase , Volker Faust
- Applicant: Roland Horres , Marita Katharina Linssen , Michael Hoffmann , Erika Hoffmann , Donate DiBiase , Volker Faust
- Applicant Address: DE Würselen
- Assignee: Hemoteq AG
- Current Assignee: Hemoteq AG
- Current Assignee Address: DE Würselen
- Agency: Meyertons, Hood, Kivlin, Kowert & Goetzel, P.C.
- Agent Eric B. Meyertons
- Priority: DE10221055 20020510
- Main IPC: A61F2/82
- IPC: A61F2/82 ; A61K31/337 ; A61K31/436 ; A61K9/00 ; A61P29/00 ; A61L31/10 ; C08L5/10 ; A61L33/08 ; A61L31/16 ; A61K31/722 ; A61K31/727 ; A61K31/095 ; A61K31/045 ; A61K31/075 ; A61K31/11 ; A61K31/12 ; A61K31/28 ; A61K31/33 ; A61K31/21 ; A61K31/13

Abstract:
The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.
Public/Granted literature
- US20110009955A1 COMPOUNDS AND METHOD FOR COATING SURFACES IN A HEMOCOMPATIBLE MANNER Public/Granted day:2011-01-13
Information query
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