Invention Grant
- Patent Title: Lipid therapy
- Patent Title (中): 脂质治疗
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Application No.: US11694793Application Date: 2007-03-30
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Publication No.: US08785382B2Publication Date: 2014-07-22
- Inventor: Deborah Kilpatrick , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Florian N. Ludwig , Paul M. Consigny , Jeffrey T. Ellis , Florencia Lim
- Applicant: Deborah Kilpatrick , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Florian N. Ludwig , Paul M. Consigny , Jeffrey T. Ellis , Florencia Lim
- Applicant Address: unknown Santa Clara
- Assignee: Abbott Cardiovascular Systems Inc.
- Current Assignee: Abbott Cardiovascular Systems Inc.
- Current Assignee Address: unknown Santa Clara
- Agency: Blakely Sokoloff Taylor & Zafman LLP
- Agent Randy Shen, Esq.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61N1/30 ; A61M31/00
Abstract:
A method including introducing into a blood stream a delipidated high density lipoprotein (HDL) and a bioactive agent. A composition including a delipidated high density lipoprotein (HDL) and an auxiliary agent in a form suitable for delivery into a blood vessel. A composition including Apo A1 comprising a hydrophobic ligand suitable to interact with cell surface binding sites. A composition including Apo A1 and an agent selected to one of increase the ATP-binding cassette protein 1 (ABCA1) transporter expression in macrophages and protect ABCA1 from thiol-mediated degradation.
Public/Granted literature
- US20070232539A1 LIPID THERAPY Public/Granted day:2007-10-04
Information query
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