发明授权
- 专利标题: Lipid therapy
- 专利标题(中): 脂质治疗
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申请号: US11694793申请日: 2007-03-30
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公开(公告)号: US08785382B2公开(公告)日: 2014-07-22
- 发明人: Deborah Kilpatrick , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Florian N. Ludwig , Paul M. Consigny , Jeffrey T. Ellis , Florencia Lim
- 申请人: Deborah Kilpatrick , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Florian N. Ludwig , Paul M. Consigny , Jeffrey T. Ellis , Florencia Lim
- 申请人地址: unknown Santa Clara
- 专利权人: Abbott Cardiovascular Systems Inc.
- 当前专利权人: Abbott Cardiovascular Systems Inc.
- 当前专利权人地址: unknown Santa Clara
- 代理机构: Blakely Sokoloff Taylor & Zafman LLP
- 代理商 Randy Shen, Esq.
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61N1/30 ; A61M31/00
摘要:
A method including introducing into a blood stream a delipidated high density lipoprotein (HDL) and a bioactive agent. A composition including a delipidated high density lipoprotein (HDL) and an auxiliary agent in a form suitable for delivery into a blood vessel. A composition including Apo A1 comprising a hydrophobic ligand suitable to interact with cell surface binding sites. A composition including Apo A1 and an agent selected to one of increase the ATP-binding cassette protein 1 (ABCA1) transporter expression in macrophages and protect ABCA1 from thiol-mediated degradation.
公开/授权文献
- US20070232539A1 LIPID THERAPY 公开/授权日:2007-10-04
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