发明授权
- 专利标题： Generation of artificial binding proteins on the basis of ubiquitin proteins
- 专利标题（中）： 在泛素蛋白的基础上生成人工结合蛋白
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申请号： US11283332申请日： 2005-11-18
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公开(公告)号： US08790895B2公开(公告)日： 2014-07-29
- 发明人: Markus Fiedler , Ulrike Fiedler , Rainer Rudolph
- 申请人： Markus Fiedler , Ulrike Fiedler , Rainer Rudolph
- 申请人地址： DE Halle/Saale
- 专利权人： Scil Proteins GmbH
- 当前专利权人： Scil Proteins GmbH
- 当前专利权人地址： DE Halle/Saale
- 代理机构： Jenkins, Wilson, Taylor & Hunt, P.A.
- 优先权： DE10324447 20030528
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N15/10 ; G01N33/68 ; C40B40/02 ; C07K14/00
摘要：
The invention relates to modified proteins of the superfamily of “ubiquitin-like proteins”, proteins that have a ubiquitin-like fold and fragments or fusion proteins thereof. As a result of said modification, the proteins have a binding affinity with respect to a predetermined binding partner that did not exist previously. The invention also relates to a method for the production and utilization of said proteins.
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