Invention Grant
- Patent Title: Aminopyrimidine derivatives as LRRK2 modulators
- Patent Title (中): 氨基嘧啶衍生物作为LRRK2调节剂
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Application No.: US13687429Application Date: 2012-11-28
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Publication No.: US08796296B2Publication Date: 2014-08-05
- Inventor: Charles Baker-Glenn , Mark Chambers , Bryan K. Chan , Anthony Estrada , Zachary Kevin Sweeney
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; A61K31/506 ; C07D239/47 ; C07D239/48
Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
Public/Granted literature
- US20130158006A1 AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS Public/Granted day:2013-06-20
Information query
IPC分类:
