发明授权
- 专利标题： Production of viruses, viral isolates and vaccines
- 专利标题（中）： 生产病毒，病毒分离物和疫苗
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申请号： US11879422申请日： 2007-07-16
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公开(公告)号： US08802417B2公开(公告)日： 2014-08-12
- 发明人: Giuseppe Marzio , Maria Grazia Pau , Dirk Jan Elbertus Opstelten , Alphonsus Gerardus Cornelis Maria Uytdehaag
- 申请人： Giuseppe Marzio , Maria Grazia Pau , Dirk Jan Elbertus Opstelten , Alphonsus Gerardus Cornelis Maria Uytdehaag
- 申请人地址： NL Leiden
- 专利权人： Crucell Holland B.V.
- 当前专利权人： Crucell Holland B.V.
- 当前专利权人地址： NL Leiden
- 代理机构： TraskBritt
- 优先权： WOPCT/NL01/00892 20011207; EP02075327 20020125
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N7/02 ; C12N7/04
摘要：
The present invention discloses methods for producing and/or propagating virus particles, such as influenza virus particles, that are present in a virus isolate obtained from an infected subject by contacting a host cell with a virus particle and culturing the cell under conditions conducive to propagation of the virus particle. The invention also provides a method for selective propagation of a set of virus particles, such as influenza virus particles present in an influenza isolate, which have an affinity for receptors comprising a specific glycosylation residue.
公开/授权文献
- US20080050403A1 Production of viruses, viral isolates and vaccines 公开/授权日：2008-02-28
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