发明授权
- 专利标题: Determination of sFlt-1:angiogenic factor complex
- 专利标题(中): sFlt-1:血管生成因子复合物的测定
-
申请号: US12350090申请日: 2009-01-07
-
公开(公告)号: US08835183B2公开(公告)日: 2014-09-16
- 发明人: George Bashirians , Deborah Byrne , Sarah Groulx , Sharon Jackson , Heather Lane-Brown , Banumathi Sankaran , Edward Scalice , Karen Yang , Jian Zheng
- 申请人: George Bashirians , Deborah Byrne , Sarah Groulx , Sharon Jackson , Heather Lane-Brown , Banumathi Sankaran , Edward Scalice , Karen Yang , Jian Zheng
- 申请人地址: US NJ Raritan
- 专利权人: Ortho-Clinical Diagnostics, Inc.
- 当前专利权人: Ortho-Clinical Diagnostics, Inc.
- 当前专利权人地址: US NJ Raritan
- 代理商 Susan J. Timian
- 主分类号: G01N33/543
- IPC分类号: G01N33/543 ; G01N33/68 ; G01N33/566
摘要:
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount of the complex can be used in methods for predicting, detecting, monitoring a disease, or guiding therapy in respect to a disease such as vascular, vascular-related disease, cardiac, cardiac-related disease, cancer, cancer-related disease, preeclampsia, and preeclampsia-related disease. Determining sFlt-1:angiogenic factor complex is particularly useful for predicting and detecting preeclampsia in early stages of gestation and in stages of the disease where clinical evaluation may be uninformative.
公开/授权文献
- US20090176247A1 Determination of sFlt-1:Angiogenic Factor Complex 公开/授权日:2009-07-09