发明授权
- 专利标题: Alpha B-crystallin as a therapy for multiple sclerosis
- 专利标题(中): αB晶状蛋白作为多发性硬化症的治疗
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申请号: US12931001申请日: 2011-01-21
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公开(公告)号: US08835391B2公开(公告)日: 2014-09-16
- 发明人: Lawrence Steinman , Shalina Sheryl Ousman , William H. Robinson
- 申请人: Lawrence Steinman , Shalina Sheryl Ousman , William H. Robinson
- 申请人地址: US CA Palo Alto
- 专利权人: The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人: The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址: US CA Palo Alto
- 代理机构: Bozicevic, Field & Francis LLP
- 代理商 Pamela J. Sherwood
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/17 ; A61K31/711
摘要:
The invention provides methods for treating inflammatory diseases by administering to the subject an effective amount of an agent that provides alpha B-crystallin activity, where the dose is effective to suppress or prevent initiation, progression, or relapses of disease, including the progression of established disease. In some embodiments, the methods of the invention comprise administering to a subject having a pre-existing inflammatory disease condition, an effective amount of alpha B-crystallin protein, to suppress or prevent relapses of the disease.
公开/授权文献
- US20110160142A1 Alpha B-Crystallin as a therapy for inflammation 公开/授权日:2011-06-30