发明授权
US08835434B2 Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors
有权
羟基化的嘧啶基环戊烷作为蛋白激酶抑制剂
- 专利标题： Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors
- 专利标题（中）： 羟基化的嘧啶基环戊烷作为蛋白激酶抑制剂
-
申请号： US12811957申请日： 2009-01-09
-
公开(公告)号： US08835434B2公开(公告)日： 2014-09-16
- 发明人: Josef R. Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mitchell , Keith Lee Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Steven Do , Jun Liang , Brian Safina , Birong Zhang
- 申请人： Josef R. Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mitchell , Keith Lee Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Steven Do , Jun Liang , Brian Safina , Birong Zhang
- 申请人地址： US CO Boulder US CA South San Francisco
- 专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人地址： US CO Boulder US CA South San Francisco
- 代理机构： Viksnins, Harris & Padys PLLP
- 国际申请： PCT/US2009/030610 WO 20090109
- 国际公布： WO2009/089459 WO 20090716
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; C07D403/04 ; A61P35/00 ; A61P25/28 ; A61P9/00 ; A61P29/00 ; A61P15/00 ; C07D239/70
摘要：
The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases, such as cancer.
公开/授权文献
信息查询
IPC分类:
