Invention Grant
US08846874B2 IgG Fc fragment for a drug carrier and method for the preparation thereof
有权
用于药物载体的IgG Fc片段及其制备方法
- Patent Title: IgG Fc fragment for a drug carrier and method for the preparation thereof
- Patent Title (中): 用于药物载体的IgG Fc片段及其制备方法
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Application No.: US10535341Application Date: 2004-11-13
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Publication No.: US08846874B2Publication Date: 2014-09-30
- Inventor: Sung Youb Jung , Jin Sun Kim , Geun Hee Yang , Se Chang Kwon , Gwan Sun Lee
- Applicant: Sung Youb Jung , Jin Sun Kim , Geun Hee Yang , Se Chang Kwon , Gwan Sun Lee
- Applicant Address: KR Hwaseong-si
- Assignee: Hanmi Science Co., Ltd
- Current Assignee: Hanmi Science Co., Ltd
- Current Assignee Address: KR Hwaseong-si
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2003-0080299 20031113
- International Application: PCT/KR2004/002942 WO 20041113
- International Announcement: WO2005/047334 WO 20050526
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/40 ; C07K14/505 ; A61K47/48 ; C07K19/00 ; C07K14/56 ; C07K14/535 ; C07K14/61 ; C07K16/46 ; C07K1/00
Abstract:
Disclosed is an IgG Fc fragment useful as a drug carrier. Also, the present invention discloses a recombinant vector expressing the IgG Fc fragment, a transformant transformed with the recombinant vector, and a method of preparing an IgG Fc fragment, comprising culturing the transformant. When conjugated to a certain drug, the IgG Fc fragment improves the in vivo duration of action of the drug and minimizes the in vivo activity reduction of the drug.
Public/Granted literature
- US20070041967A1 Igg fc fragment for a drug carrier and method for the preparation thereof Public/Granted day:2007-02-22
Information query
