发明授权
US08865686B2 Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors
有权
四环素类化合物作为酪氨酰-DNA磷酸二酯酶I抑制剂
- 专利标题: Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors
- 专利标题(中): 四环素类化合物作为酪氨酰-DNA磷酸二酯酶I抑制剂
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申请号: US12241011申请日: 2008-09-29
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公开(公告)号: US08865686B2公开(公告)日: 2014-10-21
- 发明人: Yves Pommier , Laurent Thibaut , Christophe Marchand
- 申请人: Yves Pommier , Laurent Thibaut , Christophe Marchand
- 申请人地址: US DC Washington
- 专利权人: The United States of America, as Represented by the Secretary, Dept. of Health and Human Services
- 当前专利权人: The United States of America, as Represented by the Secretary, Dept. of Health and Human Services
- 当前专利权人地址: US DC Washington
- 代理机构: Cantor Colburn LLP
- 主分类号: A61K31/65
- IPC分类号: A61K31/65 ; A61P35/00 ; C07D499/21 ; C07C237/26 ; C07D295/13
摘要:
The instant invention is directed towards tetracycline compositions, and methods of inhibiting Tdp1 activity, and methods of treating Tdp1-associated disorders.
公开/授权文献
- US20090176747A1 TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT 公开/授权日:2009-07-09
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