发明授权
US08871711B2 Fibroblast growth factor-9 promotes hair follicle regeneration after wounding
有权
成纤维细胞生长因子-9促进创伤后的毛囊再生
- 专利标题： Fibroblast growth factor-9 promotes hair follicle regeneration after wounding
- 专利标题（中）： 成纤维细胞生长因子-9促进创伤后的毛囊再生
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申请号： US13129100申请日： 2009-11-11
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公开(公告)号： US08871711B2公开(公告)日： 2014-10-28
- 发明人: George Cotsarelis , Oh Sang Kwon
- 申请人： George Cotsarelis , Oh Sang Kwon
- 申请人地址： US PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Pearl Cohen Zedek Latzer Baratz LLP
- 代理商 Mark S. Cohen
- 国际申请： PCT/US2009/064049 WO 20091111
- 国际公布： WO2010/056759 WO 20100520
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61M37/00 ; A61P17/14 ; A61Q7/00 ; A61K8/64 ; A61K38/18
摘要：
The present invention provides methods for treating hair loss, treating, inhibiting, or suppressing a degenerative skin disorder, treating androgenetic alopecia (AGA), generating new hair follicles (HF), and increasing the size of existing HF. The methods comprise epidermal disruption or administration of wnt, and administration of a fibroblast growth factor-9 polypeptide or another compound that upregulates sonic hedgehog gene signaling.
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