发明授权
- 专利标题： Surface display of recombinant proteins in lower eukaryotes
- 专利标题（中）： 重组蛋白在低等真核生物中的表达
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申请号： US12863911申请日： 2009-02-20
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公开(公告)号： US08877686B2公开(公告)日： 2014-11-04
- 发明人: Dongxing Zha , Stefan Wildt
- 申请人： Dongxing Zha , Stefan Wildt
- 申请人地址： US NH Lebanon
- 专利权人： Glycofi, Inc.
- 当前专利权人： Glycofi, Inc.
- 当前专利权人地址： US NH Lebanon
- 国际申请： PCT/US2009/034631 WO 20090220
- 国际公布： WO2009/111183 WO 20090911
- 主分类号： C40B30/04
- IPC分类号： C40B30/04 ; C12N15/10 ; C07K16/32 ; C40B40/02 ; C07K16/00 ; C07K16/28 ; C40B50/06 ; C07K16/40
摘要：
Methods for display of recombinant proteins or protein libraries on the surface of lower eukaryotes such as yeast and filamentous fungi are described. The methods are useful for screening libraries of recombinant proteins in lower eukaryotes to identify particular proteins with desired properties from the array of proteins in the libraries. The methods are particularly useful for constructing and screening antibody libraries in lower eukaryotes.
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