Invention Grant
- Patent Title: Process for producing protein A-like protein with use of Brevibacillus genus bacterium
- Patent Title (中): 使用短杆菌属细菌产生蛋白A样蛋白的方法
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Application No.: US14066231Application Date: 2013-10-29
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Publication No.: US08889389B2Publication Date: 2014-11-18
- Inventor: Akihiko Kosugi , Kazuyoshi Yajima
- Applicant: Kaneka Corporation
- Applicant Address: JP Osaka
- Assignee: Kaneka Corporation
- Current Assignee: Kaneka Corporation
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- Priority: JP2004-198831 20040706
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N11/14 ; C12N15/00 ; C12N1/20 ; C12P21/02 ; C07K16/12 ; C07K14/31

Abstract:
The present invention relates to an efficient and economical process for producing a protein A-like protein. Hosts such as Escherichia coli and Bacillus subtilis have been used in the production of a protein A-like protein using a genetic recombination technique and however, their low productivity has been a big cause of high cost. Thus, it has been desired strongly to immediately establish a technique enabling the inexpensive, large-scale production of a protein A-like protein using recombinant DNA techniques other than Escherichia coli and Bacillus subtilis. The present invention provides a process for producing a protein A-like protein in large amounts, for example, a process comprising allowing a recombinant Brevibacillus genus bacterium to express and secrete the protein in large amounts into a culture solution and separating and collecting the accumulated protein A-like protein from the culture solution.
Public/Granted literature
- US20140080179A1 PROCESS FOR PRODUCING PROTEIN A-LIKE PROTEIN WITH USE OF BREVIBACILLUS GENUS BACTERIUM Public/Granted day:2014-03-20
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