发明授权
US08916607B2 Use of piperphentonamine or salts thereof in manufacture of medicaments for treating brain diseases
有权
胡椒胺或其盐在制备用于治疗脑部疾病的药物中的用途
- 专利标题： Use of piperphentonamine or salts thereof in manufacture of medicaments for treating brain diseases
- 专利标题（中）： 胡椒胺或其盐在制备用于治疗脑部疾病的药物中的用途
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申请号： US13498272申请日： 2009-10-20
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公开(公告)号： US08916607B2公开(公告)日： 2014-12-23
- 发明人: Huayin Wan , Rubing Li , Lijian Zhou , Tieqiu Liu , Yangshu Chen , Yonghe Li
- 申请人： Huayin Wan , Rubing Li , Lijian Zhou , Tieqiu Liu , Yangshu Chen , Yonghe Li
- 申请人地址： CN Guangdong
- 专利权人： Guangzhou Municipal Zhongwei Biotechnology Limited Company
- 当前专利权人： Guangzhou Municipal Zhongwei Biotechnology Limited Company
- 当前专利权人地址： CN Guangdong
- 代理机构： Buchanan, Ingersoll & Rooney PC
- 优先权： CN200910307637 20090924
- 国际申请： PCT/CN2009/074526 WO 20091020
- 国际公布： WO2011/035500 WO 20110331
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; A61K31/36 ; A61K31/357
摘要：
The present invention relates to the use of piperphentonamine or pharmaceutically acceptable salts thereof to prevent/treat encephalopathy in mammals, and the use of a combination of piperphentonamine or pharmaceutically acceptable salts thereof and other medicines in manufacture a medicine to prevent/treat encephalopathy in mammals. The mammals include human beings, and the encephalopathy includes cerebral injury related diseases or cerebrovascular diseases. The cerebrovascular diseases refer to cerebral ischemia, cerebral ischemia/reperfusion-induced injury or cerebral hemorrhage. The cerebral hemorrhage includes hypertensive cerebral hemorrhage, cerebral hemorrhage secondary to infarction, tumor cerebral hemorrhage or cerebral hemorrhage caused by arteritis. The cerebral ischemia means carotid system cerebral ischemia or vertebrobasilar cerebral ischemia.