发明授权
- 专利标题： Antigen binding proteins to oncostatin M (OSM)
- 专利标题（中）： 抗原结合蛋白与制瘤素M（OSM）
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申请号： US13989191申请日： 2011-11-21
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公开(公告)号： US08916695B2公开(公告)日： 2014-12-23
- 发明人: Gary Peter Bembridge , Chun-Wa Chung , Maria Feeney , Susannah Karen Ford , Ian Kirby , Ruth McAdam
- 申请人： Gary Peter Bembridge , Chun-Wa Chung , Maria Feeney , Susannah Karen Ford , Ian Kirby , Ruth McAdam
- 申请人地址： GB
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB
- 代理商 Jason C. Fedon; William T. Han
- 国际申请： PCT/EP2011/070604 WO 20111121
- 国际公布： WO2012/069433 WO 20120531
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07K16/00 ; C07K16/24
摘要：
The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanizing antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
公开/授权文献
- US20130251724A1 ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) 公开/授权日：2013-09-26
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