Invention Grant
- Patent Title: Prolyl hydroxylase inhibitors and methods of use
- Patent Title (中): 脯氨酰羟化酶抑制剂及其使用方法
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Application No.: US14062011Application Date: 2013-10-24
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Publication No.: US08940773B2Publication Date: 2015-01-27
- Inventor: Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
- Applicant: Akebia Therapeutics, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Akebia Therapeutics, Inc.
- Current Assignee: Akebia Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Jones Day
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07D213/81 ; C07D213/65 ; C07D405/10 ; C07D401/04 ; C07D401/10 ; A61K31/44 ; C07D417/04 ; C07C235/60 ; C07C237/42 ; C07C255/57 ; C07D295/192

Abstract:
The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
Public/Granted literature
- US20140045899A1 PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE Public/Granted day:2014-02-13
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