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公开(公告)号：US20170189387A1
公开(公告)日：2017-07-06
申请号：US15420617
申请日：2017-01-31
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A61K31/4418 , A61K31/4433
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04 , Y02A50/401
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：US20150119425A1
公开(公告)日：2015-04-30
申请号：US14568200
申请日：2014-12-12
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: C07D213/81 , C07D405/04
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04 , Y02A50/401
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
Abstract translation: 本公开内容涉及HIF-1α脯氨酰羟化酶抑制剂，其包含本文所述的HIF-1α脯氨酰羟化酶抑制剂的组合物以及用于控制外周血管疾病（PVD），冠状动脉疾病（CAD），心力衰竭， 缺血和贫血。
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公开(公告)号：US20190192494A1
公开(公告)日：2019-06-27
申请号：US16119146
申请日：2018-08-31
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A61K31/4418 , C07C237/42 , A61K31/4433 , C07D417/04 , C07D405/10 , C07D213/81 , C07C255/57 , C07D213/65 , C07C235/60 , C07D401/10 , C07D401/04 , C07D295/192 , C07D405/04
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：USRE47437E1
公开(公告)日：2019-06-18
申请号：US15875495
申请日：2018-01-19
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: C07D417/04 , C07D405/10 , C07D295/192 , C07D213/65 , C07C237/42 , C07C255/57 , C07C235/60 , C07D213/81 , C07D401/04 , C07D405/04 , C07D401/10 , A61K31/4418 , A61K31/4433
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：US08940773B2
公开(公告)日：2015-01-27
申请号：US14062011
申请日：2013-10-24
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: C07D405/04 , C07D213/81 , C07D213/65 , C07D405/10 , C07D401/04 , C07D401/10 , A61K31/44 , C07D417/04 , C07C235/60 , C07C237/42 , C07C255/57 , C07D295/192
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
Abstract translation: 本公开内容涉及HIF-1α脯氨酰羟化酶抑制剂，其包含本文所述的HIF-1α脯氨酰羟化酶抑制剂的组合物以及用于控制外周血管疾病（PVD），冠状动脉疾病（CAD），心力衰竭， 缺血和贫血。
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Patent Agency Ranking
公开(公告)号：US20240358691A1
公开(公告)日：2024-10-31
申请号：US18537481
申请日：2023-12-12
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04 , Y02A50/30
Abstract: The present disclosure relates to HIF-la prolyl hydroxylase inhibitors, compositions which comprise the HIF-la prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：US20230201178A1
公开(公告)日：2023-06-29
申请号：US17815391
申请日：2022-07-27
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A61K31/4418 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/81 , C07D213/65 , C07D405/10 , C07D405/04 , C07D295/192 , C07D401/04 , C07D401/10 , C07D417/04 , A61K31/4433
CPC classification number: A61K31/4418 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/81 , C07D213/65 , C07D405/10 , C07D405/04 , C07D295/192 , C07D401/04 , C07D401/10 , C07D417/04 , A61K31/4433 , Y02A50/30
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：US08598210B2
公开(公告)日：2013-12-03
申请号：US13681876
申请日：2012-11-20
Applicant: Akebia Therapeutics Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Namal C. Warshakoon , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer
IPC: A01N43/40 , A61K31/44 , C07D213/62 , C07D213/78 , C07D405/00
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
Abstract translation: 本公开内容涉及HIF-1α脯氨酰羟化酶抑制剂，其包含本文所述的HIF-1α脯氨酰羟化酶抑制剂的组合物以及用于控制外周血管疾病（PVD），冠状动脉疾病（CAD），心力衰竭， 缺血和贫血。
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公开(公告)号：US20210137901A1
公开(公告)日：2021-05-13
申请号：US16908092
申请日：2020-06-22
Applicant: Akebia Therapeutics, Inc.
Inventor： Richard Masaru Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A61K31/4418 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/81 , C07D213/65 , C07D405/10 , C07D405/04 , C07D295/192 , C07D401/04 , C07D401/10 , C07D417/04 , A61K31/4433
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
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公开(公告)号：US08722895B2
公开(公告)日：2014-05-13
申请号：US13859574
申请日：2013-04-09
Applicant: Akebia Therapeutics Inc.
Inventor： Richard M. Kawamoto , Shengde Wu , Artem G. Evdokimov , Kenneth D. Greis , Angelique Sun Boyer , Namal C. Warshakoon
IPC: A01N43/40 , A61K31/44 , C07D213/62 , C07D213/78 , C07D211/70 , C07D211/82 , C07D213/46 , C07D213/90 , C07D213/00
CPC classification number: A61K31/4418 , A61K31/4433 , C07C235/60 , C07C237/42 , C07C255/57 , C07D213/65 , C07D213/81 , C07D295/192 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D417/04
Abstract: The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
Abstract translation: 本公开内容涉及HIF-1α脯氨酰羟化酶抑制剂，其包含本文所述的HIF-1α脯氨酰羟化酶抑制剂的组合物以及用于控制外周血管疾病（PVD），冠状动脉疾病（CAD），心力衰竭， 缺血和贫血。
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