Invention Grant
- Patent Title: Bivalent ligands for the treatment of neurological disorders
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Application No.: US14371075Application Date: 2013-01-10
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Publication No.: US08946254B2Publication Date: 2015-02-03
- Inventor: Yan Zhang , Kurt F. Hauser , Dana E. Selley
- Applicant: Virginia Commonwealth University
- Applicant Address: US VA Richmond
- Assignee: Virginia Commonwealth University
- Current Assignee: Virginia Commonwealth University
- Current Assignee Address: US VA Richmond
- Agency: Whitham Curtis Christofferson & Cook, PC
- International Application: PCT/US2013/020966 WO 20130110
- International Announcement: WO2013/106528 WO 20130718
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/08
Abstract:
Bivalent ligands that contain two pharmacophores linked through a spacer, one of which interacts with the μ-opioid receptor (MOR) and the other of which interacts with the co-receptor CC chemokine receptor 5 (CCR5), are used for the treatment of neurological disorders such as those associated with AIDS.
Public/Granted literature
- US20140357656A1 Bivalent Ligands for the Treatment of Neurological Disorders Public/Granted day:2014-12-04
Information query
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