发明授权
- 专利标题： Fused pyrimidines
- 专利标题（中）： 融合嘧啶
-
申请号： US13201277申请日： 2010-02-02
-
公开(公告)号： US08957064B2公开(公告)日： 2015-02-17
- 发明人: Matthias Vennemann , Thomas Bär , Thomas Maier , Swen Hölder , Gerrit Beneke , Florian Dehmel , Armin Zülch , Andreas Strub , Thomas Beckers , Stuart Ince , Hartmut Rehwinkel , Ningshu Liu , Ulf Bömer
- 申请人： Matthias Vennemann , Thomas Bär , Thomas Maier , Swen Hölder , Gerrit Beneke , Florian Dehmel , Armin Zülch , Andreas Strub , Stuart Ince , Hartmut Rehwinkel , Ningshu Liu , Ulf Bömer , Barbara Beckers
- 申请人地址： US DE Monheim
- 专利权人： Bayer Intellectual Property GmbH
- 当前专利权人： Bayer Intellectual Property GmbH
- 当前专利权人地址： US DE Monheim
- 优先权： EP09075072 20090213; EP09152914 20090216
- 国际申请： PCT/EP2010/000620 WO 20100202
- 国际公布： WO2010/091808 WO 20100819
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K31/519 ; A61K31/505 ; C07D401/12 ; C07D487/04 ; A61K45/06 ; C07D471/04
摘要：
Compounds of formula (I) or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6, R7, m and n have the meanings as given in the description and the claims, which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
公开/授权文献
- US20130317002A1 FUSED PYRIMIDINES 公开/授权日：2013-11-28
信息查询
