Invention Grant
- Patent Title: Benzofuran derivatives
- Patent Title (中): 苯并呋喃衍生物
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Application No.: US13255366Application Date: 2010-03-09
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Publication No.: US08957069B2Publication Date: 2015-02-17
- Inventor: Tetsuya Tsukamoto , Takeshi Wakabayashi , Taiichi Ohra
- Applicant: Tetsuya Tsukamoto , Takeshi Wakabayashi , Taiichi Ohra
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2009-056719 20090310
- International Application: PCT/JP2010/054286 WO 20100309
- International Announcement: WO2010/104194 WO 20100916
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/541 ; A61K31/5377 ; A61K31/519 ; C07D307/79 ; C07D307/80 ; C07D307/81 ; C07D405/06 ; C07D405/14 ; C07D487/04 ; C07D413/12 ; C07D491/113 ; C07D417/06 ; C07D413/06 ; C07D493/10 ; C07D405/04 ; C07D405/12 ; C07D407/04 ; C07D407/12 ; C07D417/12 ; A61K31/551 ; C07D413/04

Abstract:
The present invention provides a compound represented by the following formula (I): wherein: Ring A represents an optionally substituted piperazine ring, an optionally substituted morpholine ring, or an optionally substituted bromopiperazine ring; R1 and R2 are the same or different from each other, and represent a hydrogen atom or optionally substituted lower alkyl; R3 and R4 are the same or different from each other, and represent a hydrogen atom or halogenated or non-halogenated lower alkyl; R3 to R7 are the same or different from each other, and represent a hydrogen atom, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkoxy, optionally substituted cycloalkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic ring, optionally substituted amino, or acyl; and represents a single bond or double bond, wherein R2 and R3 do not exist when carbon atoms respectively adjacent to R2: and R3 form a double bond, and there is no case where all of R1 to R7 are hydrogen atoms, and R1 and R2; may form a ring together with an adjacent carbon atom; or a salt thereof.
Public/Granted literature
- US20120046277A1 BENZOFURAN DERIVATIVES Public/Granted day:2012-02-23
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