Invention Grant
US08962692B2 Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
有权
半胱氨酸和胱氨酸前药用于治疗精神分裂症并减少药物渴求
- Patent Title: Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
- Patent Title (中): 半胱氨酸和胱氨酸前药用于治疗精神分裂症并减少药物渴求
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Application No.: US13465383Application Date: 2012-05-07
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Publication No.: US08962692B2Publication Date: 2015-02-24
- Inventor: James M. Cook , David A. Baker , Wenyuan Yin , Edward Merle Johnson, II
- Applicant: James M. Cook , David A. Baker , Wenyuan Yin , Edward Merle Johnson, II
- Applicant Address: US WI Milwaukee US WI Milwaukee
- Assignee: Marquette University,UWM Research Foundation, Inc.
- Current Assignee: Marquette University,UWM Research Foundation, Inc.
- Current Assignee Address: US WI Milwaukee US WI Milwaukee
- Agency: Quarles & Brady, LLP
- Main IPC: A61K31/095
- IPC: A61K31/095 ; A61K31/105 ; C07C323/03 ; C07C323/64 ; C07C327/34 ; C07C323/60 ; C07D241/08 ; C07D487/04 ; C07K5/062
Abstract:
The present invention discloses cysteine prodrugs having the general formula: cystine dimers of the cysteine prodrugs having the general formula: protected cysteine analogs having the general formula: and dimers of the protected cysteine analogs having the general formula: The invention further encompasses pharmaceutical compositions containing the disclosed prodrugs, dimers, and analogs, and methods of using such compounds for treatment of schizophrenia and drug addiction.
Public/Granted literature
- US20120220596A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS Public/Granted day:2012-08-30
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