发明授权
US08987480B2 Process of separating chiral isomers of chroman compounds and their derivatives and precursors
有权
分离色满化合物及其衍生物和前体的手性异构体的方法
- 专利标题: Process of separating chiral isomers of chroman compounds and their derivatives and precursors
- 专利标题(中): 分离色满化合物及其衍生物和前体的手性异构体的方法
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申请号: US14116880申请日: 2012-05-08
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公开(公告)号: US08987480B2公开(公告)日: 2015-03-24
- 发明人: Gerhard Schiefer , Thomas Netscher , Alexander Lucia Leonardus Duchateau
- 申请人: Gerhard Schiefer , Thomas Netscher , Alexander Lucia Leonardus Duchateau
- 申请人地址: NL Heerlen
- 专利权人: DSM IP Assets B.V.
- 当前专利权人: DSM IP Assets B.V.
- 当前专利权人地址: NL Heerlen
- 代理机构: Nixon & Vanderhye P.C.
- 优先权: EP11165442 20110510
- 国际申请: PCT/EP2012/058415 WO 20120508
- 国际公布: WO2012/152779 WO 20121115
- 主分类号: C07D311/76
- IPC分类号: C07D311/76 ; C07D311/04 ; C07B55/00 ; C07B57/00 ; C07D311/22 ; C07D311/72
摘要:
The present invention relates to a process of separating chiral isomers of chroman compounds, particularly tocopherols and tocotrienols as well as the esters and intermediates thereof. It has been found that this process allows a separation of the desired isomer with a higher yield and enables the use of the non-desired isomers in a very efficient way. Said process is particularly useful when implemented in an industrial process. Furthermore, it has been found that this process allows using isomer mixtures as they result from traditional industrial synthesis.
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