发明授权
- 专利标题： Uniform field magnetization and targeting of therapeutic formulations
- 专利标题（中）： 均匀场磁化和靶向治疗剂型
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申请号： US12653465申请日： 2009-12-15
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公开(公告)号： US09028829B2公开(公告)日： 2015-05-12
- 发明人: Robert J. Levy , Michael Chorny , Vladimir Muzykantov , Elizabeth Hood
- 申请人： Robert J. Levy , Michael Chorny , Vladimir Muzykantov , Elizabeth Hood
- 申请人地址： US PA Philadelphia
- 专利权人： The Children's Hospital of Philadelphia
- 当前专利权人： The Children's Hospital of Philadelphia
- 当前专利权人地址： US PA Philadelphia
- 代理机构： RatnerPrestia
- 主分类号： A61K39/44
- IPC分类号： A61K39/44 ; A61N2/10 ; A61M31/00 ; A61K9/50 ; A61K9/51 ; A61K47/42 ; A61K47/48 ; A61K48/00 ; A61L31/16 ; C12N15/11 ; C12N15/86
摘要：
Systems and methods for magnetic targeting of therapeutic particles are provided. Therapeutic particles comprise one or more magnetic or magnetizable materials and at least one therapeutic agent. Therapeutic particles are specifically targeted using uniform magnetic fields capable of magnetizing magnetizable materials, and can be targeted to particular locations in the body, or can be targeted for capture, containment, and removal. Therapeutic particles can comprise antioxidant enzymes, and can be targeted to cells to protect the cells from oxidative damage.
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