发明授权
- 专利标题： Pyrimidines as novel therapeutic agents
- 专利标题（中）： 嘧啶类作为新型治疗剂
-
申请号： US12784975申请日： 2010-05-21
-
公开(公告)号： US09040538B2公开(公告)日： 2015-05-26
- 发明人: Giorgio Attardo , Sasmita Tripathy , Martin Gagnon
- 申请人： Giorgio Attardo , Sasmita Tripathy , Martin Gagnon
- 申请人地址： CA Laval
- 专利权人： Universite Laval
- 当前专利权人： Universite Laval
- 当前专利权人地址： CA Laval
- 代理机构： Clark & Elbing LLP
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; A61K31/506 ; A61K31/435 ; C07D239/38 ; C07D403/14 ; C07D213/02 ; C07D239/56 ; C07D401/12 ; C07D403/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D487/04 ; C07D513/04
摘要：
The present invention features compounds having the Formula (Ia) and (Ib) (e.g., a compound of any of Formulas ((Ia-2)-(Ia-21)), including other tautomers, stereoisomers, E/Z stereoisomers, prodrugs, pharmaceutically acceptable salts, and compositions thereof. The invention also features methods for treating or preventing pain (e.g., neuropathic pain), inflammation, or epilepsy in a patient by administering an effective amount of a compound of Formula (Ia) or (Ib). The invention also features a method for treating or preventing pain (e.g., neuropathic pain), inflammation, or epilepsy in a patient that includes administering to a patient in need thereof an effective amount of a compound of Formula (IIa) or (IIb) (e.g., a compound of any of Formulas ((IIa-2)-(IIa-6)). The compounds described herein (e.g., a compound of Formulas (Ia), (Ib), (IIa), or (IIb)) can also be used as anticonvulsants.
公开/授权文献
- US20100298336A1 PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS 公开/授权日：2010-11-25
信息查询
IPC分类:
