Invention Grant
US09056097B2 Composite of amorphous calcium phosphate/calcium sulfate hemihydrate (CSH/ACP) for bone implantation and process for producing the same
有权
用于骨植入的无定形磷酸钙/硫酸钙半水合物复合物(CSH / ACP)及其制备方法
- Patent Title: Composite of amorphous calcium phosphate/calcium sulfate hemihydrate (CSH/ACP) for bone implantation and process for producing the same
- Patent Title (中): 用于骨植入的无定形磷酸钙/硫酸钙半水合物复合物(CSH / ACP)及其制备方法
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Application No.: US13010473Application Date: 2011-01-20
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Publication No.: US09056097B2Publication Date: 2015-06-16
- Inventor: Jen-Chang Yang , Sheng-Yang Lee , Duen-Cheng Wang , Haw-Ming Huang , Wei-Jen Chang , Malosi Poma , Hong-Da Wu , Dian-Yu Ji
- Applicant: Jen-Chang Yang , Sheng-Yang Lee , Duen-Cheng Wang , Haw-Ming Huang , Wei-Jen Chang , Malosi Poma , Hong-Da Wu , Dian-Yu Ji
- Applicant Address: TW Taipei
- Assignee: Taipei Medical University
- Current Assignee: Taipei Medical University
- Current Assignee Address: TW Taipei
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K33/42
- IPC: A61K33/42 ; A61L27/42

Abstract:
The invention provides a composite of α-calcium sulfate (CS) hemihydrate/amorphous calcium phosphate (α-CSH/ACP), comprising α-CSH and ACP at a weight ratio of about 10:90 to about 90:10. Particularly, the composite of the invention has a resorption period of 3-6 months. The invention also provides a one-pot process for producing α-CSH/ACP composite of the invention. The one-pot process of the invention can produce α-CSH and ACP in a single process and easily obtain α-CSH/ACP composite.
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