Invention Grant
US09056886B2 Guanosine-rich modified oligonucleotides and antiproliferative activity thereof
有权
富含肌氨酸的修饰的寡核苷酸及其抗增殖活性
- Patent Title: Guanosine-rich modified oligonucleotides and antiproliferative activity thereof
- Patent Title (中): 富含肌氨酸的修饰的寡核苷酸及其抗增殖活性
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Application No.: US13381326Application Date: 2010-06-29
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Publication No.: US09056886B2Publication Date: 2015-06-16
- Inventor: Soo Jin Lee , Sung Hwan Moon
- Applicant: Soo Jin Lee , Sung Hwan Moon
- Applicant Address: KR Suwon-Si, Gyeonggi-Do
- Assignee: APTABIO THERAPEUTICS INC.
- Current Assignee: APTABIO THERAPEUTICS INC.
- Current Assignee Address: KR Suwon-Si, Gyeonggi-Do
- Agency: Lowe Hauptman & Ham, LLP
- Priority: KR10-2009-0058498 20090629; KR10-2010-0051202 20100531
- International Application: PCT/KR2010/004202 WO 20100629
- International Announcement: WO2011/002200 WO 20110106
- Main IPC: C07H19/173
- IPC: C07H19/173 ; C07H21/00
Abstract:
The present invention relates to a novel modified oligonucleotide comprising at least one guanosine molecule and a modified nucleic acid with therapeutic efficacies. The present invention also relates to a pharmaceutical composition having cell apoptotic activity against cancer cells for preventing or treating cancer comprising a guanosine-rich modified oligonucleotide with at least one therapeutically effective modified nucleic acid (N), or its pharmaceutically acceptable salt as active ingredient.
Public/Granted literature
- US20120202981A1 NOVEL GUANOSINE-RICH MODIFIED OLIGONUCLEOTIDES AND ANTIPROLIFERATIVE ACTIVITY THEREOF Public/Granted day:2012-08-09
Information query
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