A diaphragm pump (1) which has in at least one pump head (2) a working or pump diaphragm (3) which, by means of a clamping zone (4) arranged at its outer circumference, is clamped between two housing parts (5, 6) of a pump housing and which, between itself and a pump head part (6), borders a working or delivery chamber (8) and which, in a central zone (10), surrounds a diaphragm armature (11) which, on a side facing away from the working or delivery chamber (8) of the at least one pump head (2), is connected to a reciprocating drive (12) which is provided for generating an oscillating stroke movement of the working or pump diaphragm (3). The diaphragm pump according to the invention is characterized in that the annular zone arranged adjacent to the clamping zone (4) is formed as a guide zone (14) which, in the unloaded state of the working or pump diaphragm, is convexly curved and projects into the working or delivery chamber (8), with which guide zone (14) the working or pump diaphragm (3) rolls on a complementarily shaped annular or support zone (15) of the pump head (2) during the stroke movement of the working or pump diaphragm (3), and that a compensation zone (16) of the working or pump diaphragm (3) is provided between the guide zone (14) and the central zone (10), which compensation zone, in the unloaded state, is in contrast curved concavely and in the direction of the stroke drive (12). The diaphragm pump according to the invention is characterized by improved pump performance, a long service life and quiet and low-vibration pump operation.