发明授权
US09061022B2 Pharmaceutical composition for treating wounds or revitalizing skin comprising Euphorbia kansui extracts, fractions thereof or diterpene compounds separated from the fractions as active ingredient
有权
用于治疗伤口或活化皮肤的药物组合物,其包含从所述级分分离的大戟属提取物,其级分或二萜化合物作为活性成分
- 专利标题: Pharmaceutical composition for treating wounds or revitalizing skin comprising Euphorbia kansui extracts, fractions thereof or diterpene compounds separated from the fractions as active ingredient
- 专利标题(中): 用于治疗伤口或活化皮肤的药物组合物,其包含从所述级分分离的大戟属提取物,其级分或二萜化合物作为活性成分
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申请号: US14559254申请日: 2014-12-03
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公开(公告)号: US09061022B2公开(公告)日: 2015-06-23
- 发明人: Jae Wha Kim , Sei Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Ok-Kyoung Kwon , Seung Ho Kim , Jang Mi Son , Hyuk Hwan Song , Hee Gu Lee , Byeong Hwa Jeon , Da Jung Ji , Khiev Piseth
- 申请人: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- 申请人地址: KR Daejeon
- 专利权人: Korea Research Institute of Bioscience And Biotechnology
- 当前专利权人: Korea Research Institute of Bioscience And Biotechnology
- 当前专利权人地址: KR Daejeon
- 代理机构: Lucas & Mercanti, LLP
- 优先权: KR10-2012-0062231 20120611
- 主分类号: A01N65/00
- IPC分类号: A01N65/00 ; A61K36/47 ; A61K31/215 ; A61K36/00
摘要:
The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising the Euphorbia kansui extract, the fractions thereof, or the diterpene compound isolated therefrom as an active ingredient. The Euphorbia kansui extract may act on epithelial cells to induce PKD1 activity required for improving the reproduction capability of differentiated epithelial cells, and thus may induce the phosphorylation of lower ERK1 and the generation of Cycline D, thus exhibiting an excellent ability to activate the reproduction of damaged skin. Therefore, the Euphorbia kansui extract may be used effectively as an active ingredient in a pharmaceutical composition for treating wounds or reproducing skin, a health food for recovering skin damage or reproducing skin, or a functional cosmetic for inducing skin cell activity.
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