发明授权
US09061041B2 2′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
有权
2'-取代的核苷衍生物及其用于治疗病毒性疾病的方法
- 专利标题： 2′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
- 专利标题（中）： 2'-取代的核苷衍生物及其用于治疗病毒性疾病的方法
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申请号： US14111687申请日： 2012-04-11
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公开(公告)号： US09061041B2公开(公告)日： 2015-06-23
- 发明人: Vinay Girijavallabhan , F. George Njoroge , Stephane Bogen , Vishal Verma , Frank Bennett , Angela Kerekes , Ashok Arasappan , Dmitri Pissarnitski , Qun Dang , Ian Davies , David B. Olsen , Andrew Stamford , Joseph P. Vacca
- 申请人： Vinay Girijavallabhan , F. George Njoroge , Stephane Bogen , Vishal Verma , Frank Bennett , Angela Kerekes , Ashok Arasappan , Dmitri Pissarnitski , Qun Dang , Ian Davies , David B. Olsen , Andrew Stamford , Joseph P. Vacca
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Jeffrey P. Bergman; Laura M. Ginkel
- 国际申请： PCT/US2012/033017 WO 20120411
- 国际公布： WO2012/142085 WO 20121018
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; A61K31/7072 ; A61K31/7042 ; A61K31/7068 ; A61K45/06 ; C07H17/02 ; C07H19/10 ; C07H19/11 ; C07H19/207 ; C07H19/213
摘要：
The present invention relates to 2′-Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2′-Substituted Nucleoside Derivative, and methods of using the 2′-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
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