发明授权
- 专利标题: Vitamin D3 lactone derivatives
- 专利标题(中): 维生素D3内酯衍生物
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申请号: US10543881申请日: 2004-01-29
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公开(公告)号: US09073885B2公开(公告)日: 2015-07-07
- 发明人: Kazuya Takenouchi , Miyuki Anzai , Hiroshi Saito , Kazuhisa Okada , Seiichi Ishizuka , Daishiro Miura , Hiroaki Takayama , Atsushi Kittaka , Nozomi Saito , Toshie Fujishima
- 申请人: Kazuya Takenouchi , Miyuki Anzai , Hiroshi Saito , Kazuhisa Okada , Seiichi Ishizuka , Daishiro Miura , Hiroaki Takayama , Atsushi Kittaka , Nozomi Saito , Toshie Fujishima
- 申请人地址: JP Tokyo
- 专利权人: Teijin Pharma Limited
- 当前专利权人: Teijin Pharma Limited
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2003-021650 20030130; JP2003-339658 20030930
- 国际申请: PCT/JP2004/000815 WO 20040129
- 国际公布: WO2004/067525 WO 20040812
- 主分类号: A61K31/593
- IPC分类号: A61K31/593 ; C07D307/58
摘要:
A compound represented by the following Formula (1) that is effective for the treatment of Paget's disease of bone or hypercalcemia or a medically acceptable solvate thereof; [wherein R1 refers to hydrogen atom, C1-C6 alkyl group optionally substituted with hydrogen group or C1-C6 alkoxy group optionally substituted with hydroxyl group, R2a and R2b refer to hydrogen atom, C1-C10 alkyl group optionally substituted with hydroxyl group, C6-C10 aryl group optionally substituted with hydroxyl group or C7-C12 aralkyl group optionally substituted with a hydroxyl group, or are combined to represent ethylene group. However, a compound in which R1 is a hydrogen atom or a methyl group and R2a and R2b are hydrogen atoms is excluded].
公开/授权文献
- US20060148768A1 Vitamin d3 lactone derivatives 公开/授权日:2006-07-06
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