Invention Grant
- Patent Title: Assay for measurement of antibodies binding to a therapeutic monoclonal antibody
- Patent Title (中): 测定结合治疗性单克隆抗体的抗体的测定
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Application No.: US13766130Application Date: 2013-02-13
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Publication No.: US09081016B2Publication Date: 2015-07-14
- Inventor: Veit Peter Grunert , Ursula Klause , Pavel Kubalec , Matthias Rothfuss , Barbara Upmeier
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Roche Diagnostics Operations, Inc.
- Priority: EP10173408 20100819
- Main IPC: C40B30/04
- IPC: C40B30/04 ; G01N33/68
Abstract:
Methods and system for determination of an anti- antibody (anti- AB) in vitro in a sample from a patient treated with a therapeutic monoclonal antibody (TmAB). Also, methods and systems for the determination of antigen specific antibodies of a particular immunoglobulin class and for the identification of a patient who is at risk of developing an adverse drug reaction (ADR) during treatment with a TmAB.
Public/Granted literature
- US20130157892A1 ASSAY FOR MEASUREMENT OF ANTIBODIES BINDING TO A THERAPEUTIC MONOCLONAL ANTIBODY Public/Granted day:2013-06-20
Information query
