发明授权
- 专利标题: Sulfonamide derivatives
- 专利标题(中): 磺酰胺衍生物
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申请号: US14358494申请日: 2012-12-06
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公开(公告)号: US09085517B2公开(公告)日: 2015-07-21
- 发明人: David James Rawson , Robert Ian Storer , Nigel Alan Swain
- 申请人: Pfizer Limited
- 申请人地址: GB Sandwich, Kent
- 专利权人: Pfizer Limited
- 当前专利权人: Pfizer Limited
- 当前专利权人地址: GB Sandwich, Kent
- 代理商 Richard V. Zanzalari
- 国际申请: PCT/IB2012/057035 WO 20121206
- 国际公布: WO2013/088315 WO 20130620
- 主分类号: C07D307/00
- IPC分类号: C07D307/00 ; A61K31/00 ; C07C307/06 ; C07D213/89 ; C07D401/12 ; C07D205/04 ; C07D213/64 ; C07D213/65 ; C07D213/69 ; A61K31/18 ; A61K31/44 ; A61K31/4427
摘要:
The present invention relates to sulfonamide derivatives, of formula (I): or a pharmaceutically acceptable salts thereof, wherein X, Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description, and to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. The compounds of formula (I) are Nav1.7 inhibitors useful in the treatment of a wide range of disorders, particularly pain.
公开/授权文献
- US20140315879A1 Sulfonamide Derivatives 公开/授权日:2014-10-23
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