发明授权
- 专利标题: Compounds as lysophosphatidic acid receptor antagonists
- 专利标题(中): 化合物作为溶血磷脂酸受体拮抗剂
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申请号: US13498491申请日: 2010-10-01
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公开(公告)号: US09090573B2公开(公告)日: 2015-07-28
- 发明人: Thomas J Seiders , Lucy Zhao , Jeannie Arruda , Bowei Wang , Brian Andrew Stearns , Yem Pham Truong , Jill Melissa Scott , John Howard Hutchinson , Ryan Clark , Heather Renee Coate , Nicholas Simon Stock , Deborah Volkots
- 申请人: Thomas J Seiders , Lucy Zhao , Jeannie Arruda , Bowei Wang , Brian Andrew Stearns , Yem Pham Truong , Jill Melissa Scott , John Howard Hutchinson , Ryan Clark , Heather Renee Coate , Nicholas Simon Stock , Deborah Volkots
- 申请人地址: US NJ Princeton
- 专利权人: AMIRA PHARMACEUTICALS, INC.
- 当前专利权人: AMIRA PHARMACEUTICALS, INC.
- 当前专利权人地址: US NJ Princeton
- 代理机构: Hoffmann & Baron, LLP
- 国际申请: PCT/US2010/051150 WO 20101001
- 国际公布: WO2011/041694 WO 20110407
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; C07D417/12 ; C07D413/06 ; C07D413/12 ; C07D261/08 ; C07D261/14 ; A61K31/42 ; A61K31/422 ; A61K31/427 ; A61K31/4439 ; A61K31/4725 ; A61K31/4709 ; A61K31/519
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
公开/授权文献
- US20120289522A1 COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS 公开/授权日:2012-11-15
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