Invention Grant
US09102645B2 Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release
有权
化合物用于稳定来自异常水平的钙释放的兰诺定受体
- Patent Title: Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release
- Patent Title (中): 化合物用于稳定来自异常水平的钙释放的兰诺定受体
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Application No.: US14213614Application Date: 2014-03-14
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Publication No.: US09102645B2Publication Date: 2015-08-11
- Inventor: Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
- Applicant: Rosalind Franklin University of Medicine and Science
- Applicant Address: US IL North Chicago
- Assignee: Rosalind Franklin University of Medicine and Science
- Current Assignee: Rosalind Franklin University of Medicine and Science
- Current Assignee Address: US IL North Chicago
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K31/4427
- IPC: A61K31/4427 ; A61K31/341 ; A61K31/4166 ; C07D307/52 ; C07D405/12 ; C07D307/54 ; C07D407/12
Abstract:
Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
Public/Granted literature
- US20140275112A1 Compounds For Stabilizing Ryanodine Receptors From Aberrant Levels Of Calcium Release Public/Granted day:2014-09-18
Information query
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