Invention Grant
US09102730B2 Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells
有权
基于在抗原呈递细胞上表达的针对DCIR的靶向抗原的疫苗
- Patent Title: Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells
- Patent Title (中): 基于在抗原呈递细胞上表达的针对DCIR的靶向抗原的疫苗
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Application No.: US13872793Application Date: 2013-04-29
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Publication No.: US09102730B2Publication Date: 2015-08-11
- Inventor: Gerard Zurawski , Jacques F. Banchereau , Eynav Klechevsky , Sandra Zurawski , Anne-Laure Flamar
- Applicant: Baylor Research Institute
- Applicant Address: US TX Dallas
- Assignee: Baylor Research Institute
- Current Assignee: Baylor Research Institute
- Current Assignee Address: US TX Dallas
- Agency: Norton Rose Fulbright US LLP
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/145 ; A61K39/21 ; A61K39/395 ; C07K16/46 ; C07K16/28 ; B82Y5/00 ; A61K47/48 ; C12N5/0784 ; A61K39/02 ; A61K39/00
Abstract:
The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.
Public/Granted literature
- US20130295120A1 VACCINES BASED ON TARGETING ANTIGEN TO DCIR EXPRESSED ON ANTIGEN-PRESENTING CELLS Public/Granted day:2013-11-07
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