A layout method of sub-pixel renderings includes the following steps: providing an RGB pixel rendering, wherein each pixel of the RGB pixel rendering includes a plurality of sub-pixels, and the plurality of sub-pixels have different colors from each other; and when displaying a stereo image, dividing the RGB pixel rendering into a first sub-pixel rendering corresponding to a left-eye image and a second sub-pixel rendering corresponding to a right-eye image; wherein at least one of each row and each column of the first sub-pixel rendering includes R, G, and B sub-pixels, and at least one of each row and each column of the second sub-pixel rendering includes R, G, and B sub-pixels.