Invention Grant
- Patent Title: Methods and materials for the generation of regulatory T cells
- Patent Title (中): 用于产生调节性T细胞的方法和材料
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Application No.: US13689530Application Date: 2012-11-29
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Publication No.: US09119807B2Publication Date: 2015-09-01
- Inventor: Tanja Aarvak , Anne-Marie Rasmussen , Gunnar Kvalheim , Walter Gabriell Borelli Piedras , Anne Brunsvig
- Applicant: Life Technologies AS
- Applicant Address: NO Oslo
- Assignee: Life Technologies AS
- Current Assignee: Life Technologies AS
- Current Assignee Address: NO Oslo
- Priority: GB603081.1 20060215
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/00 ; C12N5/02 ; A61K31/12 ; C12N5/0783
Abstract:
Methods are disclosed for the generation of immunosuppressive regulatory T cells. The methods can include contacting a population of CD4+CD25− T cells with a T cell receptor (TCR)/CD3 activator, a TCR co-stimulator activator, and rapamycin. Kits for the generation of immunosuppressive regulatory T cells, methods of use, and cell populations are also disclosed.
Public/Granted literature
- US20130164312A1 METHODS AND MATERIALS FOR THE GENERATION OF REGULATORY T CELLS Public/Granted day:2013-06-27
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