Invention Grant
- Patent Title: Triple reuptake inhibitors and methods of their use
- Patent Title (中): 三重再摄取抑制剂及其使用方法
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Application No.: US14062626Application Date: 2013-10-24
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Publication No.: US09133117B2Publication Date: 2015-09-15
- Inventor: Liming Shao , Fengjiang Wang , Scott C. Malcolm , Michael C. Hewitt
- Applicant: SUNOVION PHARMACEUTICALS INC.
- Applicant Address: US MA Marlborough
- Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Choate Hall & Stewart LLP
- Main IPC: C07D209/44
- IPC: C07D209/44 ; C07D205/00 ; C07D217/00 ; C07D217/10 ; C07D209/52 ; C07D209/08

Abstract:
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.
Public/Granted literature
- US20140107175A1 TRIPLE REUPTAKE INHIBITORS AND METHODS OF THEIR USE Public/Granted day:2014-04-17
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