发明授权
US09133259B2 Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof
有权
软骨低聚基质蛋白(COMP) - 生长因子复合物及其用途
- 专利标题: Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof
- 专利标题(中): 软骨低聚基质蛋白(COMP) - 生长因子复合物及其用途
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申请号: US13879399申请日: 2011-09-14
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公开(公告)号: US09133259B2公开(公告)日: 2015-09-15
- 发明人: Dominik Haudenschild , Paul Di Cesare , Jasper Yik
- 申请人: Dominik Haudenschild , Paul Di Cesare , Jasper Yik
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 代理机构: Kilpatrick Townsend & Stockton LLP
- 国际申请: PCT/US2011/051610 WO 20110914
- 国际公布: WO2012/050714 WO 20120419
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/18 ; C07K14/00 ; C07K14/435 ; C07K14/475 ; C07K14/495 ; C07K14/51 ; C07K14/485 ; C07K14/78 ; A61L27/22 ; A61L27/38 ; A61L27/54 ; A61L27/58
摘要:
The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
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