发明授权
US09133487B2 Microorganisms for producing methacrylic acid and methacrylate esters and methods related thereto
有权
用于生产甲基丙烯酸和甲基丙烯酸酯的微生物及其相关方法
- 专利标题： Microorganisms for producing methacrylic acid and methacrylate esters and methods related thereto
- 专利标题（中）： 用于生产甲基丙烯酸和甲基丙烯酸酯的微生物及其相关方法
-
申请号： US13436811申请日： 2012-03-30
-
公开(公告)号： US09133487B2公开(公告)日： 2015-09-15
- 发明人: Mark J. Burk , Anthony P. Burgard , Robin E. Osterhout , Jun Sun , Priti Pharkya
- 申请人： Mark J. Burk , Anthony P. Burgard , Robin E. Osterhout , Jun Sun , Priti Pharkya
- 申请人地址： US CA San Diego
- 专利权人： GENOMATICA, INC.
- 当前专利权人： GENOMATICA, INC.
- 当前专利权人地址： US CA San Diego
- 代理机构： Kagan Binder, PLLC
- 主分类号： C12N1/12
- IPC分类号： C12N1/12 ; C12N1/20 ; C12P7/40 ; C12P19/32 ; C12P7/42 ; C12P7/62
摘要：
The invention provides a non-naturally occurring microbial organism having a methacrylic acid, methacrylate ester, 3-hydroxyisobutyrate and/or 2-hydroxyisobutyrate pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in a methacrylic acid pathway. The invention additionally provides a method for producing methacrylic acid, methacrylate ester, 3-hydroxyisobutyrate and/or 2-hydroxyisobutyrate. The method can include culturing methacrylic acid, methacrylate ester, 3-hydroxyisobutyrate and/or 2-hydroxyisobutyrate producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding a methacrylic acid pathway enzyme in a sufficient amount to produce methacrylic acid, methacrylate ester, 3-hydroxyisobutyrate and/or 2-hydroxyisobutyrate, under conditions and for a sufficient period of time to produce methacrylic acid, methacrylate ester, 3-hydroxyisobutyrate and/or 2-hydroxyisobutyrate.
公开/授权文献
信息查询
IPC分类:
