发明授权
US09144585B2 Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
有权
分离的间充质祖细胞和由此产生的细胞外基质
- 专利标题： Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
- 专利标题（中）： 分离的间充质祖细胞和由此产生的细胞外基质
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申请号： US13812552申请日： 2011-07-27
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公开(公告)号： US09144585B2公开(公告)日： 2015-09-29
- 发明人: Joseph Itskovitz-Eldor , Ronit Shtrichman , Eyal Zussman , Efrat Barak
- 申请人： Joseph Itskovitz-Eldor , Ronit Shtrichman , Eyal Zussman , Efrat Barak
- 申请人地址： IL Haifa
- 专利权人： Technion Research & Development Foundation Limited
- 当前专利权人： Technion Research & Development Foundation Limited
- 当前专利权人地址： IL Haifa
- 国际申请： PCT/IL2011/000604 WO 20110727
- 国际公布： WO2012/014205 WO 20120202
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; C12N5/0775
摘要：
Provided are methods of isolating an extracellular matrix from mesenchymal progenitor cells which are characterized by a reduced differentiation ability into an adipogenic lineage as compared to adipose-derived mesenchymal stem cells. Also provide isolated extracellular matrix and hybrid devices comprising electrospun elements and extracellular matrix which can be used for various tissue regeneration, repair and reconstruction surgeries.
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